Table 1 Alteration of some genetic elements and factors in cardiac cell Exos under different conditions

Apolipoprotein D, Apolipoprotein C3, Complement C1q, subcomponent subunit A (C1Q1A), Complement C5 (C5), Glycoprotein Ib Platelet Subunit Alpha (GP1BA), Pro-Platelet Basic Protein, HSp20, HSp60, HSp70, IL-6, Glut1, Glut4, NAD(p)H oxidase, TNF-a, Phosphatase and tensin homolog (PTEN), EGFR, Pregnancy-associated plasma protein-A, Fibronectin, Collagen, Alix, HIF-1α, TGF-β, CD63, MMP, collagen alpha-1 (I) chain precursor, heat shock cognate 71 kDa protein, angiopoietin-related protein 2 precursor, glyceraldehyde-3-phosphate dehydrogenase, serine protease HTRA1 precursor, elongation factor 1-alpha 1-like, sodium/potassium-transporting ATPase subunit alpha-1 precursor, Na, K-ATPase alpha-1 subunit, ATPase, Na + /K + transporting, alpha 1 polypeptide, isoform CRA, apolipoprotein E precursor, L-Lactate dehydrogenase A chain, L-Lactate dehydrogenase B chain, polyubiquitin-C precursor, clathrin heavy chain 1

miR-133a, miR-21, miR-423, miR-328, miR-29b, miR-208, miR-499, miR-1, miR-192, miR-1956, miR-34a, miR-134, miR-194, miR-126, miR-486, miR-3681, miR-152, miR-3681, lncRNA Zinc finger antisense 1 (ZFAS1), Cdr1 antisense (CDR1AS), lncRNA HOX antisense intergenic RNA (HOTAIR), miR-125a-5p, miR-100-5p, miR-365a-3p, miR-193b-5p, miR-99a-5p, miR-193a-5p, miR-361-5p, miR-29a-3p, miR-885-5p, miR-345-5p, miR-1246, miR-3692-5p, miR-193b-3p, miR-654-3p, miR-1260b, miR-22-3p, miR-3168, let-7d-3p, miR-6763-3p, miR-320b, miR-155, miR-206-3p, miR-199a-5p, miR-494-3p, miR-300c, miR-320, miR-17, miR-19a, miR-19b, miR-20a, miR-30v, let-7e, miR-10a, miR-27b, miR-100, miR-126-3p, miR-130a, miR-143, miR-503, miR-222,

Increased

[10, 46, 47, 141,142,143,144,145,146,147,148,149,150,151,152,153,154,155,156,157,158,159,160,161,162,163,164,165,166,167,168,169,170,171,172,173,174,175,176]

miR-197, miR-106, miR-223, miR-4520–2-3p, miR-5579-5p, miR-3681-5p, miR-212-3p, let-7f-1-3p, miR-30c-2-3p, miR-126

Reduced