Fig. 1

Tissue heterogeneity of UCMSCs and ADMSCs. (A) Surface marker analysis of UCMSCs and ADMSCs by flow cytometry. (B) Adipogenic andOsteogenetic differentiation potentials of UCMSCs and ADMSCs using Oil Red O staining and Alizarin Red staining, respectively. (C) Volcano plot displaying up- and down-regulated genes in UCMSCs and ADMSCs. Top DEGs that have been reported to be associated with angiogenesis and anti-apoptosis are labeled in the figure. (D) Bubble plot analysis showing the GO enrichment analysis of angiogenesis-related and apoptotic-related significant pathways of DEGs between UCMSCs and ADMSCs. three donors/each kind MSCs. (E) Heatmap of score showed the function level of apoptotic-related pathways between UCMSCs and ADMSCs. The color of each square indicates the scaled score level of each pathway. The columns showed each sample, while the rows showed each pathway