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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Mesenchymal stem cells protect the integrity of the alveolar epithelial barrier through extracellular vesicles by inhibiting MAPK-mediated necroptosis

Fig. 1

Intratracheal MenSC transplantation alleviates LPS-induced ALI in vivo. (A) Schematic representation of the mouse model established in this study. PBS, LPS (4 mg/kg), and MenSCs (1 × 106 cells) were intratracheally administered to the mice. (B) Hematoxylin and eosin (H&E)-stained images of the lungs. (C) Lung injury score. (D) Destructive index (DI). (E-K) Relative mRNA expression of proinflammatory factors in the lungs of mice that were administered MenSCs in the presence of LPS (4 mg/kg) was detected via qRT‒PCR. PBS was used as a negative control

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Stem Cell Research & Therapy

ISSN: 1757-6512