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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Mesenchymal stem cells protect the integrity of the alveolar epithelial barrier through extracellular vesicles by inhibiting MAPK-mediated necroptosis

Fig. 6

MenSC-EVs ameliorate alveolar epithelial barrier dysfunction in ALI. (A) Western blot analysis of the phosphorylation of JNK, ERK NF-KB p65, MLKL, RIP1, RIP3 and the tight junction markers E-cadherin, Occludin, Claudin-1, and ZO-1 in the lung tissue of ALI mice treated with LPS and MenSC-EVs. (B) Immunofluorescence staining analysis of the localization of E-cadherin, Occludin, Claudin-1, and ZO-1 in the mouse lung

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