Tissue | % LSK+
| % LSK+CD150+CD48-CD41-
|
|---|
FL14.5 (n = 9) | 0.45 ± 0.26 *† | 0.004 ± 0.004 * |
FL17.5 (n = 8) | 0.78 ± 0.34 * | 0.011 ± 0.006 * |
FBM17.5 (n = 6) | 1.19 ± 0.57 | 0.00 ± 0.00 * |
Adult BM (n = 11) | 2.94 ± 0.70 | 0.17 ± 0.08 |
- Data shown as mean frequency of live, Lin-/low gated events. The number of independent samples evaluated as n. An asterisk (*) indicates a significant difference (P < 0.05) of LSK or LT-HSCs percentage with adult bone marrow (BM) as reference sample (Tukey and Student's t-test analysis). A dagger (†) indicates a significant difference (P < 0.05) of LSK percentage with FBM17.5 as reference sample (Tukey and Student's t-test analysis). Adult BM, four-week old adult bone marrow; FBM17.5, fetal bone marrow at day 17.5 of gestation; LSK, Lineage- Sca-1+ c-Kit+; LT-HSC, Long Term-Hematopoietic Stem Cells.
