Figure 11

Proposed mechanisms underlying the effects of DPP4-deficient on impairment of angiogenesis, endothelial function and circulating endothelial progenitor cell number based on the findings of the present study. eNOS, endothelial nitric oxide synthase; EPC, endothelial progenitor cell; G-CSF, granulocyte colony-stimulating factor; NO, nitric oxide; SDF, stromal cell-derived factor; VEGF, vascular endothelial growth factor; vWF, von Willebrand factor.