Figure 1

Improved morphology after liver irradiation with or without transplantation of mobilized CD34 + hematopoietic stem cells (HSCs). Representative photomicrographs of the liver at 7 or 21 days after irradiation in (a) Group 1 (G1), (b) Group 2 (G2), and (c) Group 3 (G3) mice. (d) Seven days after irradiation, the extent of liver degeneration/necrosis (arrow) was not significantly different between (e) G1 and (f) G2 mice. Twenty-one days after irradiation, however, areas of liver degeneration/necrosis were smaller in (g) G1 mice compared with those in (h) G2 mice. Paraffin-embedded sections were processed for hematoxylin and eosin staining. Original magnification, ×20.